Program
19 - 22 February 2009
Royal Orchid Sheraton Hotel & Towers
Bangkok, Thailand
Day One, Thursday, February 19, 2009
7:00 AM Registration desk opens
| 10:00 - 10:10 AM |
Opening Remarks & Introduction of Keynote Frederick Hayden Stuart S. Richardson Professor of Clinical Virology, Professor of Medicine and Pathology, University of Virginia School of Medicine,Charlottesville, Virginia, USA |
| 10:10 - 10:55 AM | Keynote Speaker - Lessons Learned in Studying Influenza and Other Respiratory Viruses Robert B. Couch, Baylor College of Medicine, Houston, Texas, USA |
Session I
Epidemiology/Impact
10:55 -11:2AM |
ARI Impact and Surveillance: China Hongjie Yu, Chinese Center for Disease Control and Prevention, Beijing, China |
| 11:20-11:45 AM |
ARI Impact and Surveillance: Bangladesh W. Abdulla Brooks, Division of Health and Infectious Diseases, Mohakali, Dhaka, Bangladesh |
| 11:45 - 12:10 PM | ARI Impact and Surveillance: Cambodia Sirenda Vong, Institute Pasteur Network, Cambodia |
| 12:10 - 12:35 PM | ARI Impact and Surveillance: Thailand Kumnuan Ungchusak, Director, Bureau of Epidemiology MOPH Thailand (invited) |
| 12:35 - 1:00 PM | Validating Disease Burden Estimates for Respiratory Virus Infections S.S. Chiu, Hong Kong University, SAR Hong Kong, China |
| 1:00 - 3:45 PM | Mid-Day Break |
| 3:45 - 4:10 PM | Swine, Horse and Dog Influenza Virus: Threat to Humans Gregory Gray, University of Iowa, College of Public Health, Iowa, USA |
| 4:10 - 4:25 PM |
Oral Presentation: Prospective Cohort Study of Avian Influenza Transmission in Cambodia and Thailand Khuntirat Benjawan, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand |
4:25 -4:40 PM |
Oral Presentation: Findings of a Cluster Randomized Controlled Trial of Face Masks and Hand Hygiene to Prevent Influenza Transmission in Households Benjamin J. Cowling, School of Public Health, the University of Hong Kong, Hong Kong SAR, China |
| 4:40 - 4:55 PM |
Oral Presentation: A Prospective Cohort Study of the Seasonality and Burden of Pediatric Influenza in Nicaragua Aubree Gordon, Division of Epidemiology, School of Public Health, University of California, Berkeley, California, USA |
4:55 - 5:40 PM |
How Respiratory Viruses are Spread and How to Stop Transmission Arnold Monto, University of Michigan, Ann Arbor, Michigan, USA |
5:40 - 6:10 PM |
Coffee Break |
| 6:10 - 6:25 PM |
Oral Presentation: Preexisting Immunity to Diverse Respiratory Adenovirus Serotypes Among Young Adults in the United States David Metzgar, Department of Respiratory Disease Research, Naval Health Research Center, San Diego, California, USA |
| 6:25 - 6:40 PM |
Oral Presentation: Social Contact Patterns in Vietnam and Modeling the Transmission of Respiratory Infections Peter Horby, Oxford University Clinical Research Unit, Vietnam and Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, United Kingdom |
| 6:40 - 6:55 PM |
Oral Presentation: Young Investigator Award The Genesis and Evolution of Adamantane Resitant A/H3N2 Influenza A Viruses Martha I. Nelson, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA |
| 6:55 - 7:25 PM | Poster Review - Albert Osterhaus, Erasmus MC, Rotterdam, The Netherlands |
| 7:25 - 9:25 PM | Welcoming Reception |
Day Two Friday, February 20, 2009
Session II:
Minisymposium on H5N1 Animal/Human Interface
| Session II Chairmen |
Minisymposium on H5N1 Animal/Human Interface: Chairs: Tawee Chotpitayasunondh, Queen Sirikit National Institute of Child Health Department of Medical Services, Ministry of Public Health, Bangkok, Thailand Menno de Jong, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands |
| 8:30-8:55 AM | H5N1 in Non-avian Species Albert Osterhaus, Erasmus MC, Rotterdam, The Netherlands |
| 8:55-9:20 AM |
Poultry Vaccine Efficacy in H5N1 David Swayne, USDA, Athens, Georgia, USA |
| 9:20-10:20 AM |
Country-specific experiences |
| Indonesia (15 min): Sardikin Giri Putro, Sulianti Saroso Hospital for Infectious Diseases, Jakarta, Indonesia |
|
| Vietnam (15 min): Nguyen Tran Hien, The National Institute for Hygiene and Epidemiology, Hanoi, Vietnam |
|
| Egypt (15 min): (to be determined) |
|
| China (15 min): Cuiling Xu, Chinese Center for Disease Control and Prevention, Beijing, China |
|
| 10:20-10:50 AM | Panel Discussion |
| 10:50-11:20 AM |
COFFEE BREAK |
Session III:
Virology and Diagnostics
11:20-11:45 AM |
Update on H5N1 and Influenza Diagnostics Michael Perdue, BARDA, Washington, DC, USA |
11:45-12:10 PM |
Review of Diagnostic Test
Platforms for Detection of Respiratory Pathogens Nancy Cox, Director, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA |
| 12:10-12:35 PM |
Overview of Adenovirus 14 and other Adenovirus Infections Larry Anderson, CDC, Atlanta, Georgia, USA |
| 12:35-1:00 PM |
New Insights into Rhinovirus Evolution and Detection Caroline Tapparel, University of Geneva, Switzerland |
| 1:00 - 1:15 PM |
Oral Presentation: Antiviral Control of Influenza in Aged-Care Facilities in Sydney Region Over 3 Seasons Robert Booy, National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease, The Children's Hospital at Westmead and The University of Sydney, New South Wales, Australia; and Academic Unit of Child Health, Queen Mary's School of Medicine and Dentistry at Barts and the London, London, United Kingdom |
| 1:15 - 1:30 PM |
Oral Presentation: Genetic Clustering of Human Rhinovirus Strains in Infants with Severe Bronchiolitis Glaucia Paranhos-Baccala, Emerging Pathogens Laboratory, Fondation MÈrieux, Lyon, France |
| 1:30 - 1:45 PM |
Oral Presentation: Young Investigator Award Development of a Multiplexed luminex xMap Assay for Serotype Specific Detection of Five Human Adenoviruses that Cause Respiratory Illness Cicely Washington, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA |
| 1:45-4:30 PM |
MID-DAY BREAK |
Session IV:
Pathogenesis
| 4:30-4:50 PM |
Pre-Clinical Papers Literature Review – SARS & Influenza Malik Peiris, Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China |
| 4:50-5:10 PM |
Pre-Clinical Papers Literature Review – Rhinovirus and Other Respiratory Viruses Sebastian Johnston, Heart and Lung Institute, Imperial College, London, United Kingdom |
5:10-5:35 PM |
Mechanism of Lung Injuries and Pulmonary Inflammation Joseph Mizgerd, Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, Massachusetts, USA |
| 5:35-6:00 PM |
Influenza Virus Receptor Interactions James Paulson, Scripps Institute, La Jolla, California, USA |
| 6:00 - 6:20 PM |
Coffee Break |
| 6:20-6:45 PM |
Viral Bacterial Interactions John McCullers, St. Jude Children’s Research Hospital, Memphis, Tennessee, USA |
| 6:45 - 7:00 PM |
Oral Presentation: Ocular Infections of Mice with Influenza A (H7) Viruses: A Site of Primary Virus Replication and Spread to the Respiratory Tract Jessica Belser, Immunology and Pathogenesis Branch, Influenza Division, CCID, CDC, Atlanta, Georgia, USA and Department of Microbiology, Mount Sinai School of Medicine, New York City, New York, USA |
| 7:00 - 7:15 PM |
Oral Presentation: Young Investigator Award The PB1-F2 Protein of Influenza A Virus Modulates the Early Immune Response Leading to Increased Pathogenesis in the Mouse Model Gina Conenello, Department of Microbiology, Mount Sinai School of Medicine, New York, USA |
| 7:15 - 7:30 PM |
Oral Presentation: Young Investigator Award Rhinovirus Infection Augments Recruitment of Th2 Allergen Specific T Cells to the Airway Ross Walton, Department of Respiratory Medicine, Imperial College London. United Kingdom |
| 7:30-9:00 PM |
Poster Session Wine & Cheese Reception |
Day Three, Saturday, February 21, 2009
Session V:
Clinical
8:30-8:50 AM |
Literature Review: Clinical Papers Adults Frederick Hayden, Stuart S. Richardson Professor of Clinical Virology, Professor of Medicine and Pathology, Medicine, Charlottesville, Virginia, USA |
| 8:50-9:10 AM |
Literature Review: Clinical Papers Children Tawee Chotpitayasunondh, Queen Sirikit, National Institute of Child Health, Department of Medical Services of Public Health, Bangkok, Thailand |
| 9:10-9:55 AM |
Emerging Infectious Diseases Research in Southeast Asia Sangkot Marzuki, Eijkman Institute of Molecular Biology, Jakarta, Indonesia |
| 9:55-10:20 AM |
Influenza in Transplant Patients Mike Ison, Northwestern University, Evanston, Illinois, USA |
| 10:20-10:45 AM |
Respiratory Viral Infections in Lung Transplant Recipients Laurent Kaiser, University of Geneva, Switzerland |
| 10:45-11:15 AM |
COFFEE BREAK |
| 11:15-11:30 AM |
Oral Presentation: Safety and Efficacy of Multiple-Day Treatment with Intravenous Peramivir or Oral Oseltamivir in Hospitlaized Adults with Acute Influenza Michael Ison, Northwestern University, Chicago, Illinois, USA |
| 11:30-11:45 AM |
Oral Presentation: A Cell Culture (Vero) Derived H5N1 Whole Virus Vaccine Induces Cross-Reactive Memory Responses Otfried Kistner, Biomedical Research Center, Baxter Innovations GmbH, Orth/Donau, Austria |
| 11:45-12:00 PM |
Oral Presentation: Clinical Features of Human Influenza A (H5N1) Infection in Vietnam: 2004-2006 Peter Horby, Oxford University Clinical Research Unit, Vietnam and Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, United Kingdom |
12:00-3:00 PM |
MID-DAY BREAK |
Session VI:
Vaccinology and Prevention
| 3:00-3:30 PM |
Insights into Influenza Pathogenesis and Prevention Yoshi Kawaoka, University of Wisconsin, Madison, Wisconsin, USA and University of Tokyo, Japan |
| 3:30-4:00 PM |
Pandemic Preparedness: Updated WHO Guidance Keiji Fukuda, GIP, WHO, Geneva, Switzerland |
| 4:00-4:30 PM |
Methodologies of Assessing Influenza Vaccine Effectiveness David Shay, CDC, Atlanta, Georgia, USA |
| 4:30-5:00 PM |
Overview of H5 Vaccines Wendy Keitel, Baylor College of Medicine, Houston, Texas, USA |
| 5:00 -5:15 PM |
Oral Presentation: Anti-Influenza Serum and Mucosal Antibody Responses After Administration of Live Attenuated or Inactivated Influenza Vaccines to HIV-Infected Children Myron Levin, University of Colorado-Denver, Aurora, Colorado, USA |
| 5:15 -5:30 PM |
Oral Presentation: Vaccination Approaches to Combat Human Metapneumovirus Lower Respiratory Tract Infections Sander Herfst, Department of Virology, Erasmus MC, Rotterdam, The Netherlands |
| 5:00-6:00 PM | COFFEE BREAK |
6:00- 6:15 PM |
Oral Presentation: Paradoxical Generalized Decrease of Influenza-Specific T-cell Responses in HIV-Infected Children After Administration of Inactivated Influenza Vaccine and Sporadic Decrease After Live Attenuated Influenza Vaccine Adriana Weinberg, University of Colorado-Denver, Aurora, Colorado, USA |
| 6:15-6:30 PM |
Oral Presentation: Cross-reactive Immunity of Influenza A/H5N1 Strains in Mice and Humans Inca Kusters, sanofi pasteur, Marcy LíEtoile, France |
| 6:30-6:45 PM |
Oral Presentation: An Early Report from a Randomized Controlled Trial of Nonpharmaceutical Interventions to Reduce Household Influenza Transmission; the Bangkok HITS Study Piyarat Suntarattiwong, Queen Sirikit National Institute of Child Health, Bangkok, Thailand |
| 6:45-7:00 PM | Oral Presentation: Nature and Impact of Influenza Antigen Specific T Cell Responses on Disease in an In Vivo Human Challenge Model John Oxford, Reroscreen Virology Ltd., London, United Kingdom |
| 7:00-7:15 PM | Oral Presentation: Safety and Immunogenicity of an AS03-adjuvanted H5N1 Prepandemic Influenza Vaccine – Prasert Auewarakul, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand |
| 7:15-7:30 PM | Oral Presentation: Maternal Influenza immunization and Birth Weights M.C. Steinhoff, Cincinnati Children’s Hospital and Medical Center, Global Health Center, Cincinnati, Ohio, USA |
Session VII:
Day Four - Sunday, February 22, 2009
Antivirals and Therapeutics
8:30-9:00 AM |
Update on Antiviral Resistance in H1N1 Frederick Hayden, Stuart S. Richardson Professor of Clinical Virology, Professor of Medicine and Pathology, University of Virginia School of Medicine, Charlottesville, Virginia, USA |
| 9:00-9:30 AM |
Drug Therapy for H5 Disease in Southeast Asia Menno de Jong, Head Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, The Netherlands |
| 9:30-10:00 AM |
Novel Agents for Adenoviruses Karl Hostetler, University of California – San Diego, La Jolla, California, USA |
| 10:00-10:30 AM |
Drugs Inhibiting Both Host Responses and Virus Replication Stephan Ludwig, Institut für Molekulare Virology, Westfaelische Wilhelms University Muenster, Muenster, Germany |
| 10:30-11:20 AM |
Updates on Antivirals Peramivir - W. James Alexander, BioCryst Pharmaceuticals, Inc., Cary, North Carolina, USA T705 Compound Tsutmo Sakurai, Toyama Chemical Co., Ltd., Toyama, Japan CS-8958, a Long Acting Neuraminidase Inhibitor (LANI) for Influenza Makoto Yamashita, Daiichi Sankyo Co., Ltd., Tokyo, Japan |
| 11:20-11:50 AM |
COFFEE BREAK |
| 11:50-12:20 AM |
Update on siRNA John DiVincenzo, University of Tennessee, Memphis, Tennessee, USA |
| 12:20-12:35 PM | Oral Presentation: Oseltamivir Prophylaxis Significantly Reduces the Incidence of Seasonal Influenza Infection in Immuno-Compromised Patients Northwestern University, Chicago, Illinois, USA |
| 12:35-12:20 PM |
Oral Presentation: Combinations of Immunomodulators and Specific Antivirals: A New Treatment Paradigm for Influenza Ralf Altmeyer, CombinatoRx Singapore, Helios, Singapore |
| 12:50-1:05 PM |
Oral Presentation: Cystus052 a New Compound Against Seasonal and Pandemic Influenza Virus Oliver Planz, Friedrich-Loeffler-Institut, Institute of Immunology, T¸bingen, Germany |
| 1:05-1:20 PM |
Oral Presentation: Oseltamivir Pharmacokinetics in Vietnamese Patients with Severe Human and H5N1 Avian Influenza Walter Taylor, Oxford University Clinical Research Unit, Hanoi, Vietnam and Centre for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom |
| 1:20-1:35 PM |
Oral Presentation: Young Investigator Award Characterization of Influenza H1N1 Viruses Resitant to Oseltamivir Angie Lackenby, Respiratory Virus Unit, Centre for Infection, Health Protection Agency, London, United Kingdo |
| 11:05-1:35 PM |
Closing Remarks Frederick Hayden, Nancy Cox, Tawee Chotpitayasunondh |
